Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2220182..2220840 Replicon chromosome
Accession NZ_CP125986
Organism Pseudomonas rhodesiae strain 3.8

Toxin (Protein)


Gene name higB Uniprot ID A0A2G0X687
Locus tag QMY54_RS13155 Protein ID WP_034114384.1
Coordinates 2220182..2220526 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QMY54_RS13160 Protein ID WP_034099046.1
Coordinates 2220523..2220840 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY54_RS13115 2215497..2215655 + 159 WP_153529665.1 hypothetical protein -
QMY54_RS13120 (QMY54_02624) 2215955..2216242 - 288 WP_034099056.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
QMY54_RS13125 (QMY54_02625) 2216348..2216821 - 474 WP_034114380.1 hypothetical protein -
QMY54_RS13130 (QMY54_02626) 2217022..2217654 + 633 WP_143506428.1 hypothetical protein -
QMY54_RS13135 (QMY54_02627) 2218143..2218574 - 432 WP_052229582.1 helix-turn-helix domain-containing protein -
QMY54_RS13140 (QMY54_02628) 2218719..2218874 + 156 WP_143506426.1 Arc family DNA-binding protein -
QMY54_RS13145 (QMY54_02629) 2218948..2219178 + 231 WP_236238667.1 DUF3077 domain-containing protein -
QMY54_RS13150 (QMY54_02630) 2219256..2220059 + 804 WP_034114382.1 phage antirepressor KilAC domain-containing protein -
QMY54_RS13155 (QMY54_02631) 2220182..2220526 + 345 WP_034114384.1 toxin Toxin
QMY54_RS13160 (QMY54_02632) 2220523..2220840 + 318 WP_034099046.1 transcriptional regulator Antitoxin
QMY54_RS13165 (QMY54_02633) 2220892..2221317 - 426 WP_005789662.1 helix-turn-helix domain-containing protein -
QMY54_RS13170 (QMY54_02634) 2221416..2221652 + 237 WP_034099043.1 YdaS family helix-turn-helix protein -
QMY54_RS13175 (QMY54_02635) 2221738..2221857 - 120 Protein_2021 IS5/IS1182 family transposase -
QMY54_RS13180 (QMY54_02636) 2222077..2222928 + 852 WP_034114387.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2201373..2228971 27598
- flank IS/Tn - - 2221735..2221857 122


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(46-95)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13172.02 Da        Isoelectric Point: 9.6563

>T282510 WP_034114384.1 NZ_CP125986:2220182-2220526 [Pseudomonas rhodesiae]
MKTVFFEMTSFTATVGDYLTDDEYRQLQTEMQANPEAGDVMPRTGGFRKLRWQDTRRGKGKRGGLRVIYYWLLNDGQFWM
FSIYDKDEMANLTAAQEKALKAAIDAELKKRGGK

Download         Length: 345 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12040.96 Da        Isoelectric Point: 10.1426

>AT282510 WP_034099046.1 NZ_CP125986:2220523-2220840 [Pseudomonas rhodesiae]
MKKKRDLFAELMQGVNEMGEHRQGKITLRQYEVEALAPPEVTAAEIVSIRENLHMSQPVFARQIRTSPDTLKNWEQSKSK
PNAQAALLIKLVQRFPDMVERLNAV

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G0X687

Antitoxin

Source ID Structure

References