Detailed information of TA system TA028251

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1057419..1057668
• Replicon: chromosome
• Accession: NC_018608
• Organism: Staphylococcus aureus 08BA02176

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: C248_RS05185
• Protein ID: WP_000623369.1
• Coordinates: 1057419..1057526 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1057521..1057668 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C248_RS05160	1054093..1054662	-	570	WP_000287265.1	competence protein ComK	-
C248_RS05165	1054872..1055090	+	219	WP_000876826.1	IDEAL domain-containing protein	-
C248_RS05170	1055171..1056157	-	987	WP_000668814.1	lipoate--protein ligase	-
C248_RS05175	1056356..1056532	+	177	WP_000214898.1	YkvS family protein	-
C248_RS05180	1056547..1057149	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
C248_RS05185	1057419..1057526	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1057521..1057668	-	148	-	-	Antitoxin
C248_RS05190	1058161..1058445	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
C248_RS05195	1058489..1060453	+	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
C248_RS05200	1060456..1060776	+	321	WP_000668623.1	YxeA family protein	-
C248_RS05205	1060773..1061414	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
C248_RS14275	1061502..1061792	-	291	WP_001796515.1	hypothetical protein	-
C248_RS14280	1061882..1062070	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
C248_RS05215	1062159..1062515	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T28251 WP_000623369.1 NC_018608:1057419-1057526 [Staphylococcus aureus 08BA02176]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T28251 NC_018608:1057419-1057526 [Staphylococcus aureus 08BA02176]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT28251 NC_018608:c1057668-1057521 [Staphylococcus aureus 08BA02176]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin