Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 5358642..5359314 Replicon chromosome
Accession NZ_CP125961
Organism Pseudomonas brassicacearum strain R401

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QLH64_RS23245 Protein ID WP_057449633.1
Coordinates 5358949..5359314 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QLH64_RS23240 Protein ID WP_057449632.1
Coordinates 5358642..5358956 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH64_RS23220 (QLH64_23220) 5354021..5354740 + 720 WP_057449629.1 protocatechuate 3,4-dioxygenase subunit beta -
QLH64_RS23225 (QLH64_23225) 5354753..5355355 + 603 WP_057449630.1 protocatechuate 3,4-dioxygenase subunit alpha -
QLH64_RS23230 (QLH64_23230) 5355667..5358021 + 2355 WP_236712350.1 hypothetical protein -
QLH64_RS23235 (QLH64_23235) 5358058..5358519 + 462 WP_018607342.1 Lrp/AsnC family transcriptional regulator -
QLH64_RS23240 (QLH64_23240) 5358642..5358956 - 315 WP_057449632.1 XRE family transcriptional regulator Antitoxin
QLH64_RS23245 (QLH64_23245) 5358949..5359314 - 366 WP_057449633.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QLH64_RS23250 (QLH64_23250) 5359678..5361360 + 1683 WP_057449634.1 NAD(P)/FAD-dependent oxidoreductase -
QLH64_RS23255 (QLH64_23255) 5361373..5362167 + 795 WP_057449635.1 carbon-nitrogen hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-86)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14198.91 Da        Isoelectric Point: 5.5738

>T282502 WP_057449633.1 NZ_CP125961:c5359314-5358949 [Pseudomonas brassicacearum]
MKWGVEYTDEFELWWDRLSESEQDSVQVSVMLLGDTGPYLGFPHTSDIKGSRHGNLRELRVQHAGRPYRVLYAFDPRRCA
ILLIGGDKTGQDRWYQQYVPLAERLYDEHLEVLKREGFDHG

Download         Length: 366 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11911.70 Da        Isoelectric Point: 9.6213

>AT282502 WP_057449632.1 NZ_CP125961:c5358956-5358642 [Pseudomonas brassicacearum]
MAKKFSDLMARRSPDSQARAQALYQQLRAEMPLHELRQAQELSQEALAKALHINQAAVSKMERRTDMYISTLRNYIRAMG
GELEIIATFPEGQVRIENFSHPIP

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References