Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4744221..4744876 Replicon chromosome
Accession NZ_CP125961
Organism Pseudomonas brassicacearum strain R401

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QLH64_RS20350 Protein ID WP_236712404.1
Coordinates 4744640..4744876 (-) Length 79 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QLH64_RS20345 Protein ID WP_003205391.1
Coordinates 4744221..4744535 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH64_RS20325 (QLH64_20325) 4739786..4740961 - 1176 WP_057451768.1 aspartate aminotransferase family protein -
QLH64_RS20330 (QLH64_20330) 4741061..4741978 + 918 WP_057451769.1 LysR family transcriptional regulator -
QLH64_RS20335 (QLH64_20335) 4742186..4743199 + 1014 WP_057451770.1 sensor domain-containing diguanylate cyclase -
QLH64_RS20340 (QLH64_20340) 4743304..4744008 + 705 WP_003205390.1 hypothetical protein -
QLH64_RS20345 (QLH64_20345) 4744221..4744535 - 315 WP_003205391.1 helix-turn-helix domain-containing protein Antitoxin
QLH64_RS20350 (QLH64_20350) 4744640..4744876 - 237 WP_236712404.1 hypothetical protein Toxin
QLH64_RS20355 (QLH64_20355) 4745016..4745903 - 888 WP_003178131.1 heme o synthase -
QLH64_RS20360 (QLH64_20360) 4745915..4746250 - 336 WP_003205394.1 cytochrome o ubiquinol oxidase subunit IV -
QLH64_RS20365 (QLH64_20365) 4746251..4746877 - 627 WP_057451771.1 cytochrome o ubiquinol oxidase subunit III -
QLH64_RS20370 (QLH64_20370) 4746881..4748911 - 2031 WP_057451772.1 cytochrome o ubiquinol oxidase subunit I -
QLH64_RS20375 (QLH64_20375) 4748915..4749862 - 948 WP_057451773.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(47-87)


Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9501.85 Da        Isoelectric Point: 9.8136

>T282501 WP_236712404.1 NZ_CP125961:c4744876-4744640 [Pseudomonas brassicacearum]
MRTLFFETTTFTDTVGHYLTDDEYRLLQSYMLQHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQF

Download         Length: 237 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11771.76 Da        Isoelectric Point: 9.8409

>AT282501 WP_003205391.1 NZ_CP125961:c4744535-4744221 [Pseudomonas brassicacearum]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References