Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1831942..1832591 Replicon chromosome
Accession NZ_CP125947
Organism Comamonas sp. ZM22

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QMY55_RS08615 Protein ID WP_283488211.1
Coordinates 1832253..1832591 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QMY55_RS08610 Protein ID WP_283488210.1
Coordinates 1831942..1832256 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY55_RS08565 (QMY55_08565) 1827153..1827542 + 390 WP_283488201.1 hypothetical protein -
QMY55_RS08570 (QMY55_08570) 1827547..1828608 + 1062 WP_283488202.1 hypothetical protein -
QMY55_RS08575 (QMY55_08575) 1828608..1829057 + 450 WP_283488203.1 hypothetical protein -
QMY55_RS08580 (QMY55_08580) 1829054..1829479 + 426 WP_283488204.1 DUF4128 domain-containing protein -
QMY55_RS08585 (QMY55_08585) 1829492..1829695 + 204 WP_283488205.1 hypothetical protein -
QMY55_RS08590 (QMY55_08590) 1829789..1830514 + 726 WP_283488206.1 hypothetical protein -
QMY55_RS08595 (QMY55_08595) 1830620..1831048 + 429 WP_283488207.1 hypothetical protein -
QMY55_RS08600 (QMY55_08600) 1831524..1831706 + 183 WP_283488208.1 DUF2158 domain-containing protein -
QMY55_RS08605 (QMY55_08605) 1831732..1831932 - 201 WP_283488209.1 hypothetical protein -
QMY55_RS08610 (QMY55_08610) 1831942..1832256 - 315 WP_283488210.1 transcriptional regulator Antitoxin
QMY55_RS08615 (QMY55_08615) 1832253..1832591 - 339 WP_283488211.1 toxin Toxin
QMY55_RS08620 (QMY55_08620) 1832745..1833125 - 381 WP_283488212.1 Arc family DNA-binding protein -
QMY55_RS08625 (QMY55_08625) 1833491..1834504 + 1014 WP_283488213.1 BRO family protein -
QMY55_RS08630 (QMY55_08630) 1834596..1835066 + 471 WP_283488214.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1796280..1844247 47967


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13058.87 Da        Isoelectric Point: 9.6389

>T282488 WP_283488211.1 NZ_CP125947:c1832591-1832253 [Comamonas sp. ZM22]
MKAVFVELPAFERYRSDYLDDENFRSLQHSLMKNPEAGDVIEGTGGLRKVRHADPRRGKGKRGGLRVIYYWWDGKGQFWL
FTLYDKDEMDDLSSKQKAALKSMLKAELEARQ

Download         Length: 339 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11894.79 Da        Isoelectric Point: 10.6822

>AT282488 WP_283488210.1 NZ_CP125947:c1832256-1831942 [Comamonas sp. ZM22]
MTKRDIFAELTEGFDALKEQRSGKRTLRTHEVAIKPEVEIKAAEIVTLRDSLGLSRAVFARYLRTNPRTLENWEQGRAKP
NAQAALIMRMVEKFPDTVQRLAVV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References