Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1678761..1679273 Replicon chromosome
Accession NZ_CP125946
Organism Rothia sp. SD9660Na

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QM007_RS07915 Protein ID WP_237186795.1
Coordinates 1678761..1679015 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QM007_RS07920 Protein ID WP_237197118.1
Coordinates 1679019..1679273 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM007_RS07905 (QM007_07905) 1674829..1676136 - 1308 WP_283489458.1 tyrosine--tRNA ligase -
QM007_RS07910 (QM007_07910) 1676339..1678639 - 2301 WP_283489459.1 AAA family ATPase -
QM007_RS07915 (QM007_07915) 1678761..1679015 - 255 WP_237186795.1 Txe/YoeB family addiction module toxin Toxin
QM007_RS07920 (QM007_07920) 1679019..1679273 - 255 WP_237197118.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QM007_RS07925 (QM007_07925) 1679427..1679978 - 552 WP_283489460.1 adenine phosphoribosyltransferase -
QM007_RS07930 (QM007_07930) 1679988..1681430 - 1443 WP_283489461.1 argininosuccinate lyase -
QM007_RS07935 (QM007_07935) 1681551..1682753 - 1203 WP_283489462.1 argininosuccinate synthase -
QM007_RS07940 (QM007_07940) 1682976..1683374 + 399 WP_283489463.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10184.60 Da        Isoelectric Point: 8.0688

>T282486 WP_237186795.1 NZ_CP125946:c1679015-1678761 [Rothia sp. SD9660Na]
MKIVWDENAWEDYLWWQQQDRKVLKRINTLIKDIARNGHEGIGKPEALKHDWSGFWSRRITDEHRLIYAITDTSILIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9657.95 Da        Isoelectric Point: 4.8894

>AT282486 WP_237197118.1 NZ_CP125946:c1679273-1679019 [Rothia sp. SD9660Na]
MKTMTYSESRARYAEVMDSVINDREEVVITRVGHDPVVMLSLEDYESLKEAAYLMRSPRNARRISDSIARLKAGLGEEHQ
LIEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References