Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 468319..468839 Replicon chromosome
Accession NZ_CP125946
Organism Rothia sp. SD9660Na

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QM007_RS02400 Protein ID WP_283490397.1
Coordinates 468319..468576 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QM007_RS02405 Protein ID WP_283490398.1
Coordinates 468585..468839 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM007_RS02380 (QM007_02380) 464134..465402 - 1269 WP_283490392.1 AMP-binding protein -
QM007_RS02385 (QM007_02385) 465510..465686 + 177 WP_283490393.1 hypothetical protein -
QM007_RS02390 (QM007_02390) 465690..465917 + 228 WP_283490395.1 hypothetical protein -
QM007_RS02395 (QM007_02395) 465989..468193 - 2205 WP_283490396.1 acyltransferase family protein -
QM007_RS02400 (QM007_02400) 468319..468576 - 258 WP_283490397.1 Txe/YoeB family addiction module toxin Toxin
QM007_RS02405 (QM007_02405) 468585..468839 - 255 WP_283490398.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QM007_RS02410 (QM007_02410) 469070..470023 - 954 WP_283490399.1 1,4-dihydroxy-2-naphthoyl-CoA synthase -
QM007_RS02415 (QM007_02415) 470063..470200 + 138 WP_283490400.1 hypothetical protein -
QM007_RS02420 (QM007_02420) 470215..471714 - 1500 WP_283490401.1 sodium/proline symporter PutP -
QM007_RS02425 (QM007_02425) 471940..472878 - 939 WP_283490402.1 EamA family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10284.69 Da        Isoelectric Point: 10.2335

>T282483 WP_283490397.1 NZ_CP125946:c468576-468319 [Rothia sp. SD9660Na]
VELIWSSQAWEDYLWWQKQDRKVLKRINTLLRDIQRNGNEGIGKPEALRNNLSGYWSRRITEEHRLVYKIVGNSVRIAAV
RYHYE

Download         Length: 258 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9266.37 Da        Isoelectric Point: 4.1712

>AT282483 WP_283490398.1 NZ_CP125946:c468839-468585 [Rothia sp. SD9660Na]
MKTMTYTESRANYAQVLDIAVEDLEEVVITRTGREPAVILSLAEYESLKETAHLLRSPANARRLLDSIDELEASGGSSQA
LLED

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References