Detailed information of TA system TA282471

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1964993..1965173
• Replicon: chromosome
• Accession: NZ_CP125903
• Organism: Staphylococcus aureus strain CHAL1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: QM337_RS09545
• Protein ID: WP_001801861.1
• Coordinates: 1964993..1965088 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1965116..1965173 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QM337_RS09515	1960137..1960763	+	627	WP_000669038.1	hypothetical protein	-
QM337_RS09520	1960804..1961148	+	345	WP_000627550.1	DUF3969 family protein	-
QM337_RS09525	1961246..1961818	+	573	WP_000414222.1	hypothetical protein	-
QM337_RS09530	1961967..1963334	-	1368	WP_001093574.1	FRG domain-containing protein	-
QM337_RS09535	1963334..1963903	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
QM337_RS09540	1964096..1964542	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
QM337_RS09545	1964993..1965088	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1965116..1965173	-	58	-	-	Antitoxin
QM337_RS09550	1965211..1965312	+	102	WP_001791232.1	hypothetical protein	-
QM337_RS09555	1965487..1965929	-	443	Protein_1881	DUF1433 domain-containing protein	-
QM337_RS09560	1965929..1966372	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
QM337_RS09565	1966372..1966814	-	443	Protein_1883	DUF1433 domain-containing protein	-
QM337_RS09570	1967339..1969759	+	2421	WP_283531521.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T282471 WP_001801861.1 NZ_CP125903:1964993-1965088 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT282471 NZ_CP125903:c1965173-1965116 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin