282465

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2459907..2460091 Replicon chromosome
Accession NZ_CP125901
Organism Staphylococcus aureus strain CHAL2

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag QM338_RS12370 Protein ID WP_000482652.1
Coordinates 2459984..2460091 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2459907..2459967 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM338_RS12355 2455362..2455493 - 132 WP_223197975.1 hypothetical protein -
QM338_RS12360 2455760..2457493 - 1734 WP_000486487.1 ABC transporter ATP-binding protein -
QM338_RS12365 2457518..2459281 - 1764 WP_001064825.1 ABC transporter ATP-binding protein -
- 2459907..2459967 + 61 - - Antitoxin
QM338_RS12370 2459984..2460091 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
QM338_RS12375 2460225..2460611 - 387 WP_283512296.1 flippase GtxA -
QM338_RS12380 2460879..2462021 + 1143 WP_031765234.1 glycerate kinase -
QM338_RS12385 2462081..2462740 + 660 WP_000831298.1 membrane protein -
QM338_RS12390 2462922..2464133 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
QM338_RS12395 2464256..2464729 - 474 WP_283512297.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T282465 WP_000482652.1 NZ_CP125901:c2460091-2459984 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT282465 NZ_CP125901:2459907-2459967 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References