282462

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2176725..2176941 Replicon chromosome
Accession NZ_CP125901
Organism Staphylococcus aureus strain CHAL2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QM338_RS10880 Protein ID WP_001802298.1
Coordinates 2176837..2176941 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2176725..2176780 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM338_RS10855 2172931..2173596 - 666 WP_001024095.1 SDR family oxidoreductase -
QM338_RS10860 2173748..2174068 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QM338_RS10865 2174070..2175047 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
QM338_RS10870 2175313..2176404 + 1092 WP_000495669.1 hypothetical protein -
- 2176725..2176780 + 56 - - Antitoxin
QM338_RS10880 2176837..2176941 - 105 WP_001802298.1 hypothetical protein Toxin
QM338_RS10885 2177458..2177628 + 171 WP_001792292.1 transposase -
QM338_RS10890 2177621..2177779 + 159 WP_001792784.1 hypothetical protein -
QM338_RS10895 2178437..2179294 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
QM338_RS10900 2179362..2180144 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T282462 WP_001802298.1 NZ_CP125901:c2176941-2176837 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT282462 NZ_CP125901:2176725-2176780 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References