282452

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2425181..2425365 Replicon chromosome
Accession NZ_CP125899
Organism Staphylococcus aureus strain CHAL3

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag QM339_RS12060 Protein ID WP_000482647.1
Coordinates 2425258..2425365 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2425181..2425241 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM339_RS12040 2420767..2420934 - 168 WP_031785511.1 hypothetical protein -
QM339_RS12045 2421165..2422898 - 1734 WP_000488492.1 ABC transporter ATP-binding protein -
QM339_RS12050 2422947..2424686 - 1740 WP_001064831.1 ABC transporter ATP-binding protein -
QM339_RS12055 2425064..2425231 - 168 WP_000301894.1 hypothetical protein -
- 2425181..2425241 + 61 - - Antitoxin
QM339_RS12060 2425258..2425365 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
QM339_RS12065 2425499..2425885 - 387 WP_000779354.1 flippase GtxA -
QM339_RS12070 2426153..2427295 + 1143 WP_001176860.1 glycerate kinase -
QM339_RS12075 2427355..2428014 + 660 WP_000831298.1 membrane protein -
QM339_RS12080 2428194..2429405 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
QM339_RS12085 2429528..2430001 - 474 WP_000456491.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T282452 WP_000482647.1 NZ_CP125899:c2425365-2425258 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT282452 NZ_CP125899:2425181-2425241 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References