282441

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2489343..2489527 Replicon chromosome
Accession NZ_CP125897
Organism Staphylococcus aureus strain CHAL4

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag QM341_RS12625 Protein ID WP_000482650.1
Coordinates 2489420..2489527 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2489343..2489403 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM341_RS12610 2484873..2485040 - 168 WP_001790576.1 hypothetical protein -
QM341_RS12615 2485271..2487004 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
QM341_RS12620 2487029..2488792 - 1764 WP_045188321.1 ABC transporter ATP-binding protein -
- 2489343..2489403 + 61 - - Antitoxin
QM341_RS12625 2489420..2489527 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
QM341_RS12630 2489660..2490046 - 387 WP_000779358.1 flippase GtxA -
QM341_RS12635 2490314..2491456 + 1143 WP_001176863.1 glycerate kinase -
QM341_RS12640 2491516..2492175 + 660 WP_000831298.1 membrane protein -
QM341_RS12645 2492357..2493568 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
QM341_RS12650 2493691..2494164 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T282441 WP_000482650.1 NZ_CP125897:c2489527-2489420 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT282441 NZ_CP125897:2489343-2489403 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTACCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References