282439

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2199041..2199258 Replicon chromosome
Accession NZ_CP125897
Organism Staphylococcus aureus strain CHAL4

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QM341_RS11105 Protein ID WP_001802298.1
Coordinates 2199154..2199258 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2199041..2199096 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM341_RS11080 2195178..2195843 - 666 WP_001024094.1 SDR family oxidoreductase -
QM341_RS11085 2195995..2196315 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QM341_RS11090 2196317..2197297 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
QM341_RS11095 2197563..2198654 + 1092 WP_000495671.1 lytic regulatory protein -
- 2199041..2199096 + 56 - - Antitoxin
QM341_RS11105 2199154..2199258 - 105 WP_001802298.1 hypothetical protein Toxin
QM341_RS11110 2199419..2199902 - 484 Protein_2148 recombinase family protein -
QM341_RS11115 2199945..2201081 - 1137 WP_000115564.1 SAP domain-containing protein -
QM341_RS11120 2201370..2201462 + 93 WP_001790138.1 hypothetical protein -
QM341_RS11125 2202167..2203024 - 858 WP_000370924.1 HAD family hydrolase -
QM341_RS11130 2203092..2203874 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T282439 WP_001802298.1 NZ_CP125897:c2199258-2199154 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT282439 NZ_CP125897:2199041-2199096 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References