Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2430177..2430361 Replicon chromosome
Accession NZ_CP125895
Organism Staphylococcus aureus strain CHAL5

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag QM342_RS12055 Protein ID WP_000482652.1
Coordinates 2430254..2430361 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2430177..2430237 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM342_RS12040 2425632..2425799 - 168 WP_001789205.1 hypothetical protein -
QM342_RS12045 2426030..2427763 - 1734 WP_049307645.1 ABC transporter ATP-binding protein -
QM342_RS12050 2427788..2429551 - 1764 WP_001064837.1 ABC transporter ATP-binding protein -
- 2430177..2430237 + 61 - - Antitoxin
QM342_RS12055 2430254..2430361 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
QM342_RS12060 2430495..2430881 - 387 WP_000779357.1 flippase GtxA -
QM342_RS12065 2431150..2432292 + 1143 WP_001176863.1 glycerate kinase -
QM342_RS12070 2432352..2433011 + 660 WP_000831298.1 membrane protein -
QM342_RS12075 2433193..2434404 + 1212 WP_001191922.1 multidrug effflux MFS transporter -
QM342_RS12080 2434527..2435000 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T282426 WP_000482652.1 NZ_CP125895:c2430361-2430254 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT282426 NZ_CP125895:2430177-2430237 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References