Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2145159..2145376 Replicon chromosome
Accession NZ_CP125895
Organism Staphylococcus aureus strain CHAL5

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QM342_RS10575 Protein ID WP_001802298.1
Coordinates 2145272..2145376 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2145159..2145214 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM342_RS10550 2141353..2142018 - 666 WP_001024095.1 SDR family oxidoreductase -
QM342_RS10555 2142170..2142490 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QM342_RS10560 2142492..2143472 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
QM342_RS10565 2143738..2144829 + 1092 WP_000495683.1 hypothetical protein -
- 2145159..2145214 + 56 - - Antitoxin
QM342_RS10575 2145272..2145376 - 105 WP_001802298.1 hypothetical protein Toxin
QM342_RS10580 2145537..2146020 - 484 Protein_2042 recombinase family protein -
QM342_RS10585 2146063..2147199 - 1137 WP_000115564.1 SAP domain-containing protein -
QM342_RS10590 2147488..2147580 + 93 WP_001790138.1 hypothetical protein -
QM342_RS10595 2148285..2149142 - 858 WP_000370924.1 HAD family hydrolase -
QM342_RS10600 2149210..2149992 - 783 WP_283483101.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T282424 WP_001802298.1 NZ_CP125895:c2145376-2145272 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT282424 NZ_CP125895:2145159-2145214 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References