Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF3/-
Location 1972794..1973093 Replicon chromosome
Accession NZ_CP125895
Organism Staphylococcus aureus strain CHAL5

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag QM342_RS09625 Protein ID WP_011447039.1
Coordinates 1972917..1973093 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1972794..1972849 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM342_RS09585 1968128..1968388 + 261 WP_001791826.1 hypothetical protein -
QM342_RS09590 1968441..1968791 - 351 WP_000702263.1 complement inhibitor SCIN-A -
QM342_RS09595 1969474..1969923 + 450 WP_000727649.1 chemotaxis-inhibiting protein CHIPS -
QM342_RS09600 1970018..1970352 - 335 Protein_1851 SH3 domain-containing protein -
QM342_RS09605 1971002..1971493 - 492 WP_000919350.1 staphylokinase -
QM342_RS09610 1971684..1972439 - 756 WP_000861038.1 CHAP domain-containing protein -
QM342_RS09615 1972451..1972705 - 255 WP_000611512.1 phage holin -
QM342_RS09620 1972757..1972864 + 108 WP_001791821.1 hypothetical protein -
- 1972786..1972925 + 140 NuclAT_0 - -
- 1972786..1972925 + 140 NuclAT_0 - -
- 1972786..1972925 + 140 NuclAT_0 - -
- 1972786..1972925 + 140 NuclAT_0 - -
- 1972794..1972849 + 56 - - Antitoxin
QM342_RS09625 1972917..1973093 - 177 WP_011447039.1 type I toxin-antitoxin system toxin PepG1 Toxin
QM342_RS09630 1973243..1973539 - 297 WP_000539688.1 DUF2951 domain-containing protein -
QM342_RS09635 1973597..1973884 - 288 WP_001040261.1 hypothetical protein -
QM342_RS09640 1973931..1974083 - 153 WP_001153681.1 hypothetical protein -
QM342_RS09645 1974073..1977858 - 3786 WP_000582165.1 phage tail spike protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - scn / chp / sak / hlb / groEL 1968441..2021065 52624


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T282419 WP_011447039.1 NZ_CP125895:c1973093-1972917 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 56 bp

>AT282419 NZ_CP125895:1972794-1972849 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References