Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 410711..411213 Replicon chromosome
Accession NZ_CP125880
Organism Auritidibacter ignavus strain BABAE-7

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag QM403_RS01855 Protein ID WP_233487799.1
Coordinates 411022..411213 (-) Length 64 a.a.

Antitoxin (Protein)


Gene name HigA2 Uniprot ID -
Locus tag QM403_RS01850 Protein ID WP_283533073.1
Coordinates 410711..411016 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM403_RS01820 (QM403_01820) 405997..406383 - 387 WP_110100203.1 hypothetical protein -
QM403_RS01825 (QM403_01825) 406625..406996 - 372 WP_283532856.1 hypothetical protein -
QM403_RS01830 (QM403_01830) 407140..407916 - 777 WP_283532857.1 sulfite exporter TauE/SafE family protein -
QM403_RS01835 (QM403_01835) 408938..409702 - 765 WP_283518357.1 sulfite exporter TauE/SafE family protein -
QM403_RS01840 (QM403_01840) 409968..410342 - 375 WP_283532858.1 hypothetical protein -
QM403_RS01845 (QM403_01845) 410327..410560 - 234 WP_283532859.1 hypothetical protein -
QM403_RS01850 (QM403_01850) 410711..411016 - 306 WP_283533073.1 helix-turn-helix transcriptional regulator Antitoxin
QM403_RS01855 (QM403_01855) 411022..411213 - 192 WP_233487799.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QM403_RS01860 (QM403_01860) 411480..412205 - 726 WP_283532860.1 hypothetical protein -
QM403_RS01865 (QM403_01865) 412749..413285 - 537 WP_283532861.1 GNAT family N-acetyltransferase -
QM403_RS01870 (QM403_01870) 413298..413723 - 426 WP_110100005.1 type II toxin-antitoxin system VapC family toxin -
QM403_RS01875 (QM403_01875) 413720..413953 - 234 WP_110100006.1 Arc family DNA-binding protein -
QM403_RS01880 (QM403_01880) 414101..415186 - 1086 WP_283532862.1 redox-regulated ATPase YchF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-53)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-88)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 7512.68 Da        Isoelectric Point: 8.6796

>T282415 WP_233487799.1 NZ_CP125880:c411213-411022 [Auritidibacter ignavus]
MKELRPGSSGRSELRVLFAFDPERVAIMLIAEDKIGDWKRWYKKHISLADDLFDEHLARLRRE

Download         Length: 192 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11351.01 Da        Isoelectric Point: 9.9460

>AT282415 WP_283533073.1 NZ_CP125880:c411016-410711 [Auritidibacter ignavus]
MAKNLKNFVAEHPVDRGRVEAHKKRMLAEVRAYRLRELREQAGLTQAQLAERIGVGQRQVSKIEQGDLDSAKVGTIRSYL
EAVGGELSLEYVMGDQRMQVA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References