Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 109055..109573 Replicon chromosome
Accession NZ_CP125718
Organism Staphylococcus casei strain DSM 15096

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QMO72_RS00455 Protein ID WP_048794467.1
Coordinates 109055..109324 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QMO72_RS00460 Protein ID WP_103267874.1
Coordinates 109325..109573 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMO72_RS00435 (QMO72_00435) 105244..106062 + 819 WP_286093214.1 type II CAAX endopeptidase family protein -
QMO72_RS00440 (QMO72_00440) 106243..106791 - 549 WP_103267877.1 hypothetical protein -
QMO72_RS00445 (QMO72_00445) 106901..107731 - 831 WP_103267876.1 LysR family transcriptional regulator -
QMO72_RS00450 (QMO72_00450) 107851..109002 + 1152 WP_103267875.1 MFS transporter -
QMO72_RS00455 (QMO72_00455) 109055..109324 - 270 WP_048794467.1 Txe/YoeB family addiction module toxin Toxin
QMO72_RS00460 (QMO72_00460) 109325..109573 - 249 WP_103267874.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QMO72_RS00465 (QMO72_00465) 110064..111104 - 1041 WP_046837624.1 NAD(P)-dependent alcohol dehydrogenase -
QMO72_RS00470 (QMO72_00470) 111341..112075 - 735 WP_103267873.1 NAD-dependent protein deacylase -
QMO72_RS00475 (QMO72_00475) 112382..113692 - 1311 WP_103268041.1 YjiH family protein -
QMO72_RS00480 (QMO72_00480) 114006..114137 - 132 WP_256121772.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-88)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10409.90 Da        Isoelectric Point: 9.9708

>T282278 WP_048794467.1 NZ_CP125718:c109324-109055 [Staphylococcus casei]
MAKLNITFSPQAFDDYEYFQTKDRKMVKRINQLLKSISRDGALDGIGKPEKLVGNFSGYYSRRINQEHRLVYTVNDNAIL
VASCRYHYK

Download         Length: 270 bp


Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9535.80 Da        Isoelectric Point: 5.0878

>AT282278 WP_103267874.1 NZ_CP125718:c109573-109325 [Staphylococcus casei]
MIVKSYTYVRKHFKDMINKVNDDSDAITITTKDRNAVIMSEDNYNEIMETLYLQQNPANAKHLSESIEDLERGNVKTKDI
LI

Download         Length: 249 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References