Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 3059812..3060358 Replicon chromosome
Accession NZ_CP125669
Organism Acinetobacter sp. KCTC 92772

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QLH32_RS14565 Protein ID WP_283266785.1
Coordinates 3060083..3060358 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QLH32_RS14560 Protein ID WP_283266783.1
Coordinates 3059812..3060090 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH32_RS14545 (QLH32_14545) 3056524..3057147 + 624 WP_283266779.1 nuclease-related domain-containing protein -
QLH32_RS14550 (QLH32_14550) 3057314..3058918 + 1605 WP_283266781.1 choline dehydrogenase -
QLH32_RS14555 (QLH32_14555) 3059004..3059753 - 750 WP_283266782.1 NUDIX domain-containing protein -
QLH32_RS14560 (QLH32_14560) 3059812..3060090 - 279 WP_283266783.1 NadS family protein Antitoxin
QLH32_RS14565 (QLH32_14565) 3060083..3060358 - 276 WP_283266785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QLH32_RS14570 (QLH32_14570) 3060560..3062047 - 1488 WP_283266786.1 nicotinate phosphoribosyltransferase -
QLH32_RS14575 (QLH32_14575) 3062072..3062950 - 879 WP_283266787.1 ribose-phosphate diphosphokinase -
QLH32_RS14580 (QLH32_14580) 3063320..3064495 + 1176 WP_279959541.1 zinc-binding dehydrogenase -
QLH32_RS14585 (QLH32_14585) 3064600..3065061 - 462 WP_283266789.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(27-89)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-79)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10488.96 Da        Isoelectric Point: 5.1409

>T282273 WP_283266785.1 NZ_CP125669:c3060358-3060083 [Acinetobacter sp. KCTC 92772]
MIDDDSYAKLQQALNEDPELGDLIRASGGIRKVRWNLEHTGKSGGIRVIYYYFDNEGQIFMLLAYPKSVKDNLTDRELTV
LRKLVEELKNV

Download         Length: 276 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10498.09 Da        Isoelectric Point: 8.6989

>AT282273 WP_283266783.1 NZ_CP125669:c3060090-3059812 [Acinetobacter sp. KCTC 92772]
MSEFFDELTEALEQAIAVRKGEMPASREFSLERPNIKAIREKTGLSQVQFAKRLHISPRTLQNWEQGHRYPTGPAIALIH
IIDKNPNILTMA

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References