Detailed information of TA system TA282238

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 414993..415518
• Replicon: plasmid pRspBT04e
• Accession: NZ_CP125653
• Organism: Rhizobium sp. BT04

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: QMO82_RS33095
• Protein ID: WP_097616517.1
• Coordinates: 415246..415518 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: QMO82_RS33090
• Protein ID: WP_097616518.1
• Coordinates: 414993..415244 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QMO82_RS33080	411729..413072	-	1344	WP_183608880.1	adenylate/guanylate cyclase domain-containing protein	-
QMO82_RS33085	413576..414913	+	1338	WP_183608881.1	nucleotide sugar dehydrogenase	-
QMO82_RS33090	414993..415244	+	252	WP_097616518.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
QMO82_RS33095	415246..415518	+	273	WP_097616517.1	Txe/YoeB family addiction module toxin	Toxin
QMO82_RS33100	415543..416715	-	1173	WP_183608882.1	DUF3095 domain-containing protein	-
QMO82_RS33105	416839..417318	+	480	WP_183608883.1	class I SAM-dependent methyltransferase	-
QMO82_RS33110	417352..419142	-	1791	WP_183608884.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..540617	540617

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10818.45 Da
• Isoelectric Point: 9.4680

>T282238 WP_097616517.1 NZ_CP125653:415246-415518 [Rhizobium sp. BT04]
MKLLWTPNSWEEYEYWQKTDQKMVEKINELLRDTKRSPFKGLGKPEPLKGDLSGFWSRRILGEHRLVYCVTGKGSNQQLE
IIQCRFHYEK

Nucleotide

• Length: 273 bp

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9346.53 Da
• Isoelectric Point: 5.0066

>AT282238 WP_097616518.1 NZ_CP125653:414993-415244 [Rhizobium sp. BT04]
MAHVRLTEFRQNIATYFDQVLSSRAPLLVTRQGSEAMVLIAESEYESMQETLHLLSTPANSARLRESIGQLRNGQTIEND
PTL

Nucleotide

• Length: 252 bp