Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 473920..474614 Replicon chromosome
Accession NZ_CP125619
Organism Pseudomonas sp. PMCC200367

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QFX16_RS02180 Protein ID WP_283182652.1
Coordinates 473920..474216 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QFX16_RS02185 Protein ID WP_283182653.1
Coordinates 474213..474614 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFX16_RS02145 469600..470145 - 546 WP_283182647.1 hypothetical protein -
QFX16_RS02150 470142..470396 - 255 WP_007992314.1 acyl carrier protein -
QFX16_RS02155 470406..470666 - 261 WP_283182648.1 phosphopantetheine-binding protein -
QFX16_RS02160 470647..471456 - 810 WP_283182649.1 lysophospholipid acyltransferase family protein -
QFX16_RS02165 471432..472157 - 726 WP_129439116.1 beta-ketoacyl synthase chain length factor -
QFX16_RS02170 472512..473282 + 771 WP_283182650.1 ParA family protein -
QFX16_RS02175 473290..473724 - 435 WP_283182651.1 thioredoxin TrxC -
QFX16_RS02180 473920..474216 + 297 WP_283182652.1 type II toxin-antitoxin system HigB family toxin Toxin
QFX16_RS02185 474213..474614 + 402 WP_283182653.1 transcriptional regulator Antitoxin
QFX16_RS02190 474621..476084 - 1464 WP_283182654.1 YdiU family protein -
QFX16_RS02195 476133..479483 - 3351 WP_283182655.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(19-90)

Antitoxin

Antitoxin HigA

(16-133)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11556.34 Da        Isoelectric Point: 10.4191

>T282156 WP_283182652.1 NZ_CP125619:473920-474216 [Pseudomonas sp. PMCC200367]
MHVFTEKPIHEAKEKWPRAANALEQWYRLAKGSNPGDFAAMKSIFPATDKVGEFHVFDIGGNKLRLIAFVRYRSQKLYIK
HVLDHREYDRGKWKELRA

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15158.22 Da        Isoelectric Point: 4.5052

>AT282156 WP_283182653.1 NZ_CP125619:474213-474614 [Pseudomonas sp. PMCC200367]
MSVLIKKAAEHWEFVSPLLRKPKNEDDYDILAQALDELLEMTGDDESHPLMSLVDIIGDWIAEWDREHHPMREASGAEVL
GYMMREHGLSQSDLPGVGTQSVVSEILSGKRQLNLRQIRWLAERFGVSVETFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References