Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 477054..477748 Replicon chromosome
Accession NZ_CP125618
Organism Pseudomonas sp. PMCC200344

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QFW87_RS02200 Protein ID WP_134419711.1
Coordinates 477054..477350 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QFW87_RS02205 Protein ID WP_283182653.1
Coordinates 477347..477748 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFW87_RS02165 472734..473279 - 546 WP_283182647.1 hypothetical protein -
QFW87_RS02170 473276..473530 - 255 WP_007992314.1 acyl carrier protein -
QFW87_RS02175 473540..473800 - 261 WP_008149626.1 phosphopantetheine-binding protein -
QFW87_RS02180 473781..474590 - 810 WP_283182649.1 lysophospholipid acyltransferase family protein -
QFW87_RS02185 474566..475291 - 726 WP_129439116.1 beta-ketoacyl synthase chain length factor -
QFW87_RS02190 475646..476416 + 771 WP_283182650.1 ParA family protein -
QFW87_RS02195 476424..476858 - 435 WP_283182651.1 thioredoxin TrxC -
QFW87_RS02200 477054..477350 + 297 WP_134419711.1 type II toxin-antitoxin system HigB family toxin Toxin
QFW87_RS02205 477347..477748 + 402 WP_283182653.1 transcriptional regulator Antitoxin
QFW87_RS02210 477755..479218 - 1464 WP_283189707.1 YdiU family protein -
QFW87_RS02215 479267..482617 - 3351 WP_283189708.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(19-90)

Antitoxin

Antitoxin HigA

(16-133)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11500.23 Da        Isoelectric Point: 10.4191

>T282148 WP_134419711.1 NZ_CP125618:477054-477350 [Pseudomonas sp. PMCC200344]
MHVFTEKPIHEAKEKWPRAANALEQWYRLAKGSNPGDFAAMKSIFPATDKVGEFHVFDIGGNKLRLIAFVRYRSQKLYIK
HVLDHREYDRGKWKEGRA

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15158.22 Da        Isoelectric Point: 4.5052

>AT282148 WP_283182653.1 NZ_CP125618:477347-477748 [Pseudomonas sp. PMCC200344]
MSVLIKKAAEHWEFVSPLLRKPKNEDDYDILAQALDELLEMTGDDESHPLMSLVDIIGDWIAEWDREHHPMREASGAEVL
GYMMREHGLSQSDLPGVGTQSVVSEILSGKRQLNLRQIRWLAERFGVSVETFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References