Detailed information of TA system TA282110

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 4634393..4634650
• Replicon: chromosome
• Accession: NZ_CP125351
• Organism: Escherichia fergusonii strain XJ19MCE1

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: -
• Locus tag: QKW25_RS22795
• Protein ID: WP_196081637.1
• Coordinates: 4634393..4634545 (-)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	4634602..4634650 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QKW25_RS22765	4630256..4630966	-	711	WP_000190514.1	DUF3053 domain-containing protein	-
QKW25_RS22770	4631404..4632774	+	1371	WP_000184983.1	MFS transporter	-
QKW25_RS22775	4633024..4633314	+	291	WP_000455800.1	HTH-type transcriptional regulator	-
QKW25_RS22780	4633596..4633808	+	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
QKW25_RS22785	4633862..4634233	-	372	WP_001037803.1	membrane protein insertion efficiency factor YidD	-
QKW25_RS22790	4634345..4634416	+	72	WP_216665726.1	hypothetical protein	-
QKW25_RS22795	4634393..4634545	-	153	WP_196081637.1	type I toxin-antitoxin system toxin HokA	Toxin
-	4634602..4634650	+	49	-	-	Antitoxin
QKW25_RS22800	4634846..4635205	-	360	WP_141095883.1	hypothetical protein	-
QKW25_RS22805	4635274..4637343	-	2070	WP_001291786.1	glycine--tRNA ligase subunit beta	-
QKW25_RS22810	4637353..4638264	-	912	WP_001168544.1	glycine--tRNA ligase subunit alpha	-
QKW25_RS22815	4638360..4638659	-	300	WP_024256552.1	YsaB family lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (5-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 6015.26 Da
• Isoelectric Point: 7.7169

>T282110 WP_196081637.1 NZ_CP125351:c4634545-4634393 [Escherichia fergusonii]
MSQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQENYELAAFLACKLKE

Nucleotide

• Length: 153 bp

Antitoxin

Nucleotide

• Length: 49 bp

>AT282110 NZ_CP125351:4634602-4634650 [Escherichia fergusonii]
GCATAGAGGGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin