Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 2386710..2387254 Replicon chromosome
Accession NZ_CP125315
Organism Lacticaseibacillus rhamnosus strain k32

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag QJQ50_RS11075 Protein ID WP_080716415.1
Coordinates 2387105..2387254 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag QJQ50_RS11070 Protein ID WP_032964775.1
Coordinates 2386710..2386979 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJQ50_RS11050 (QJQ50_11050) 2382323..2383483 + 1161 Protein_2147 SpaA isopeptide-forming pilin-related protein -
QJQ50_RS11055 (QJQ50_11055) 2383513..2384286 - 774 WP_283146281.1 hypothetical protein -
QJQ50_RS11060 (QJQ50_11060) 2384656..2384895 - 240 WP_032964777.1 hypothetical protein -
QJQ50_RS11065 (QJQ50_11065) 2385229..2386131 + 903 WP_032964776.1 zinc ABC transporter substrate-binding protein -
QJQ50_RS11070 (QJQ50_11070) 2386710..2386979 + 270 WP_032964775.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QJQ50_RS11075 (QJQ50_11075) 2387105..2387254 + 150 WP_080716415.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
QJQ50_RS11080 (QJQ50_11080) 2387910..2390261 - 2352 WP_049175076.1 SEC10/PgrA surface exclusion domain-containing protein -
QJQ50_RS11085 (QJQ50_11085) 2390403..2390762 - 360 WP_032964772.1 CrcB family protein -
QJQ50_RS11090 (QJQ50_11090) 2390756..2391166 - 411 WP_032964771.1 CrcB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-47)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-71)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5511.43 Da        Isoelectric Point: 9.9308

>T282002 WP_080716415.1 NZ_CP125315:2387105-2387254 [Lacticaseibacillus rhamnosus]
MSSSSAWRGFRELHIDGVNGDWLLIYKIEPKDLILTLVKTGSHKSLLGK

Download         Length: 150 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10097.63 Da        Isoelectric Point: 6.0650

>AT282002 WP_032964775.1 NZ_CP125315:2386710-2386979 [Lacticaseibacillus rhamnosus]
MATTKKEAHLNIRIDPDLKHDAQIVANDMGIDLSTAVTMFLNQMVKDHALPFTPTSLPIDTLQAIKEGNHPEKLKKYRTP
DDMWKDLDV

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References