Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 446367..446910 Replicon chromosome
Accession NZ_CP125315
Organism Lacticaseibacillus rhamnosus strain k32

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag QJQ50_RS02105 Protein ID WP_032965546.1
Coordinates 446367..446654 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag QJQ50_RS02110 Protein ID WP_032965544.1
Coordinates 446638..446910 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJQ50_RS02075 (QJQ50_02075) 441500..441868 - 369 WP_032965551.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
QJQ50_RS02080 (QJQ50_02080) 442017..442598 - 582 WP_005691622.1 dihydroxyacetone kinase subunit DhaL -
QJQ50_RS02085 (QJQ50_02085) 442585..443604 - 1020 WP_048482627.1 dihydroxyacetone kinase subunit DhaK -
QJQ50_RS02090 (QJQ50_02090) 443798..444226 - 429 WP_005691626.1 OsmC family protein -
QJQ50_RS02095 (QJQ50_02095) 444337..444516 - 180 WP_032965548.1 hypothetical protein -
QJQ50_RS02100 (QJQ50_02100) 444734..446143 - 1410 WP_032965547.1 3'-5' exonuclease -
QJQ50_RS02105 (QJQ50_02105) 446367..446654 - 288 WP_032965546.1 type II toxin-antitoxin system YafQ family toxin Toxin
QJQ50_RS02110 (QJQ50_02110) 446638..446910 - 273 WP_032965544.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QJQ50_RS02115 (QJQ50_02115) 447024..447317 + 294 WP_005684269.1 metalloregulator ArsR/SmtB family transcription factor -
QJQ50_RS02120 (QJQ50_02120) 447399..448562 + 1164 WP_032965542.1 MFS transporter -
QJQ50_RS02125 (QJQ50_02125) 448716..449291 + 576 WP_283146272.1 DNA-3-methyladenine glycosylase I -
QJQ50_RS02130 (QJQ50_02130) 449412..449630 + 219 WP_032965537.1 hypothetical protein -
QJQ50_RS02135 (QJQ50_02135) 449759..450640 - 882 WP_005684263.1 class II fructose-1,6-bisphosphate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10869.72 Da        Isoelectric Point: 10.6953

>T282001 WP_032965546.1 NZ_CP125315:c446654-446367 [Lacticaseibacillus rhamnosus]
MMLTINRTRTFKRQFKHLLRQGKDMTKLATAIDTLQRQDRVKLASLHDHALKGAHSGERALHVAPDWLLVYKVDAEALIL
MLLATGTHRDTLNIE

Download         Length: 288 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10100.56 Da        Isoelectric Point: 5.8486

>AT282001 WP_032965544.1 NZ_CP125315:c446910-446638 [Lacticaseibacillus rhamnosus]
MEKKSRISVRIDTKTKERALHVLNSMGLDMSSAINMYLKRIGDTGELPFTPEMSFADQLQAAEADVKAGRTKSFKTVDAL
MKDLYNDVDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References