281969

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrG-as-bsrG/-
Location 4110756..4111018 Replicon chromosome
Accession NZ_CP125292
Organism Bacillus subtilis strain SRCM117797

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag QL281_RS21885 Protein ID WP_009967548.1
Coordinates 4110902..4111018 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 4110756..4110907 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QL281_RS21855 (4105928) 4105928..4106461 + 534 WP_041336408.1 SMI1/KNR4 family protein -
QL281_RS21860 (4106594) 4106594..4108396 + 1803 WP_041336409.1 LXG family T7SS effector ribonuclease toxin YobL -
QL281_RS21865 (4108406) 4108406..4108864 + 459 WP_041336410.1 type VII secretion system immunity protein YobK -
QL281_RS21870 (4108954) 4108954..4109412 + 459 WP_014479998.1 YrhA family protein -
QL281_RS21875 (4109468) 4109468..4110022 + 555 WP_041336412.1 SMI1/KNR4 family protein -
QL281_RS21880 (4110082) 4110082..4110615 + 534 WP_014479996.1 GNAT family protein -
- (4110756) 4110756..4110907 + 152 NuclAT_0 - Antitoxin
- (4110756) 4110756..4110907 + 152 NuclAT_0 - Antitoxin
- (4110756) 4110756..4110907 + 152 NuclAT_0 - Antitoxin
- (4110756) 4110756..4110907 + 152 NuclAT_0 - Antitoxin
QL281_RS21885 (4110902) 4110902..4111018 - 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
QL281_RS21890 (4111250) 4111250..4111717 + 468 WP_041336414.1 YolA family protein -
QL281_RS21895 (4111723) 4111723..4112079 + 357 WP_041336416.1 hypothetical protein -
QL281_RS21900 (4112199) 4112199..4113446 + 1248 WP_031600262.1 IS256-like element ISBsu2 family transposase -
QL281_RS21905 (4113499) 4113499..4113834 - 336 WP_041336417.1 hypothetical protein -
QL281_RS21910 (4114007) 4114007..4114339 + 333 WP_041336419.1 YolD-like family protein -
QL281_RS21915 (4114332) 4114332..4115585 + 1254 WP_283009946.1 UV damage repair protein UvrX -
QL281_RS21920 (4115687) 4115687..4116004 + 318 WP_009967545.1 sublancin immunity protein SunI -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4101997..4124970 22973
- flank IS/Tn - - 4112208..4113446 1238


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-38)


Sequences


Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T281969 WP_009967548.1 NZ_CP125292:c4111018-4110902 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp


Antitoxin


Download         Length: 152 bp

>AT281969 NZ_CP125292:4110756-4110907 [Bacillus subtilis]
TTTCTTTAATGAGAAATGCATAAAATAAAAAGACCAGGGTGTTGGCGCACCCCGGCTCTGTACAAAAAGCTGCCCGTCAA
AGGGCTTGCTCGATGTTCAATCTGCGTAGACCTAACCCTTTAAGGTTCCTAAGCTCAAGGGAAGGTCTATTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9


Antitoxin

Download structure file

References