Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1708050..1708570 Replicon chromosome
Accession NZ_CP125094
Organism Agrobacterium fabrum strain N33/94

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G6L76_RS08480 Protein ID WP_080808022.1
Coordinates 1708050..1708319 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G6L76_RS08485 Protein ID WP_080808019.1
Coordinates 1708316..1708570 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L76_RS08460 (G6L76_008460) 1703085..1704779 - 1695 WP_092731507.1 iron ABC transporter permease -
G6L76_RS08465 (G6L76_008465) 1704789..1705772 - 984 WP_080808034.1 ABC transporter substrate-binding protein -
G6L76_RS08470 (G6L76_008470) 1706078..1707322 - 1245 WP_080808028.1 PLP-dependent aminotransferase family protein -
G6L76_RS08475 (G6L76_008475) 1707596..1708045 + 450 WP_080808025.1 RbsD/FucU family protein -
G6L76_RS08480 (G6L76_008480) 1708050..1708319 - 270 WP_080808022.1 Txe/YoeB family addiction module toxin Toxin
G6L76_RS08485 (G6L76_008485) 1708316..1708570 - 255 WP_080808019.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G6L76_RS08490 (G6L76_008490) 1708709..1709728 - 1020 WP_010972004.1 ketol-acid reductoisomerase -
G6L76_RS08495 (G6L76_008495) 1709776..1710429 - 654 WP_080808016.1 TetR/AcrR family transcriptional regulator -
G6L76_RS08500 (G6L76_008500) 1710802..1711707 - 906 WP_006311840.1 AraC family transcriptional regulator -
G6L76_RS08505 (G6L76_008505) 1711897..1712943 + 1047 WP_080808012.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-88)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10611.15 Da        Isoelectric Point: 9.8742

>T281917 WP_080808022.1 NZ_CP125094:c1708319-1708050 [Agrobacterium fabrum]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGSEQRLE
IIQCRFHYL

Download         Length: 270 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9692.84 Da        Isoelectric Point: 4.6882

>AT281917 WP_080808019.1 NZ_CP125094:c1708570-1708316 [Agrobacterium fabrum]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANASRLRASMDELERDDTIERD
PTEK

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References