Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-RNAII/-
Location 2779642..2779979 Replicon chromosome
Accession NZ_CP124921
Organism Enterococcus faecalis strain EfsC12

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag QLQ56_RS13290 Protein ID WP_002396786.1
Coordinates 2779642..2779785 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2779717..2779979 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ56_RS13270 (2774759) 2774759..2774974 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
QLQ56_RS13275 (2775113) 2775113..2776105 + 993 WP_023894581.1 biotin--[acetyl-CoA-carboxylase] ligase -
QLQ56_RS13280 (2776369) 2776369..2777007 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
QLQ56_RS13285 (2777693) 2777693..2779309 + 1617 WP_047648929.1 phosphatase PAP2/LCP family protein -
QLQ56_RS13290 (2779642) 2779642..2779785 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2779929) 2779929..2779978 + 50 NuclAT_14 - -
- (2779717) 2779717..2779979 - 263 NuclAT_11 - Antitoxin
QLQ56_RS13295 (2779980) 2779980..2784671 - 4692 WP_282851328.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T281819 WP_002396786.1 NZ_CP124921:2779642-2779785 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT281819 NZ_CP124921:c2779979-2779717 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References