Detailed information of TA system TA281805

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2628580..2628803
• Replicon: chromosome
• Accession: NZ_CP124921
• Organism: Enterococcus faecalis strain EfsC12

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ56_RS12605
• Protein ID: WP_075551663.1
• Coordinates: 2628702..2628803 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2628580..2628757 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ56_RS12580 (2624227)	2624227..2625180	-	954	WP_002394760.1	siderophore ABC transporter substrate-binding protein	-
QLQ56_RS12585 (2625219)	2625219..2625974	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ56_RS12590 (2625971)	2625971..2626936	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ56_RS12595 (2626933)	2626933..2627880	-	948	WP_002359058.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ56_RS12600 (2628065)	2628065..2628517	+	453	WP_002359057.1	YueI family protein	-
- (2628543)	2628543..2628753	+	211	NuclAT_6	-	-
- (2628580)	2628580..2628757	+	178	NuclAT_5	-	Antitoxin
QLQ56_RS12605 (2628702)	2628702..2628803	-	102	WP_075551663.1	putative holin-like toxin	Toxin
- (2628977)	2628977..2629186	+	210	NuclAT_7	-	-
- (2629011)	2629011..2629190	+	180	NuclAT_4	-	-
QLQ56_RS12610 (2629135)	2629135..2629236	-	102	WP_075551663.1	putative holin-like toxin	-
QLQ56_RS12615 (2629426)	2629426..2631696	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ56_RS12620 (2631867)	2631867..2632367	+	501	WP_010709949.1	cysteine hydrolase family protein	-
QLQ56_RS12625 (2632670)	2632670..2633566	+	897	WP_002354953.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281805 WP_075551663.1 NZ_CP124921:c2628803-2628702 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 178 bp

>AT281805 NZ_CP124921:2628580-2628757 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA

Structures

Antitoxin