Detailed information of TA system TA281766

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 59411..59652
• Replicon: plasmid p1_EfsC17_rep9b
• Accession: NZ_CP124917
• Organism: Enterococcus faecalis strain EfsC17

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: QLQ62_RS14620
• Protein ID: WP_002360667.1
• Coordinates: 59411..59521 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	59561..59652 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ62_RS14575 (54637)	54637..55224	+	588	WP_010830316.1	hypothetical protein	-
QLQ62_RS14580 (55355)	55355..55951	+	597	WP_153829629.1	recombinase family protein	-
QLQ62_RS14585 (55941)	55941..56255	+	315	WP_174091296.1	hypothetical protein	-
QLQ62_RS14590 (56249)	56249..56473	+	225	WP_002414746.1	ultraviolet resistance protein UvrA repressor UvrC	-
QLQ62_RS14595 (56534)	56534..56743	+	210	WP_010822516.1	hypothetical protein	-
QLQ62_RS14600 (56755)	56755..57057	+	303	WP_002393766.1	DUF6440 family protein	-
QLQ62_RS14605 (57485)	57485..58813	+	1329	WP_002370254.1	ultraviolet resistance protein UvrA	-
QLQ62_RS14610 (58810)	58810..59160	+	351	WP_002399364.1	hypothetical protein	-
QLQ62_RS14615 (59117)	59117..59329	+	213	WP_002360669.1	hypothetical protein	-
QLQ62_RS14620 (59411)	59411..59521	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (59561)	59561..59652	-	92	NuclAT_0	-	Antitoxin
- (59561)	59561..59652	-	92	NuclAT_0	-	Antitoxin
- (59561)	59561..59652	-	92	NuclAT_0	-	Antitoxin
- (59561)	59561..59652	-	92	NuclAT_0	-	Antitoxin
QLQ62_RS14625 (59761)	59761..60057	+	297	WP_002360665.1	replication control protein PrgN	-
QLQ62_RS14630 (60311)	60311..61093	+	783	WP_174094941.1	ParA family protein	-
QLQ62_RS14635 (61086)	61086..61442	+	357	WP_282855876.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	prgB/asc10	1..61701	61701

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T281766 WP_002360667.1 NZ_CP124917:59411-59521 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 92 bp

>AT281766 NZ_CP124917:c59652-59561 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin