Detailed information of TA system TA281757

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2730121..2730383
• Replicon: chromosome
• Accession: NZ_CP124916
• Organism: Enterococcus faecalis strain EfsC17

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ62_RS13540
• Protein ID: WP_002367458.1
• Coordinates: 2730240..2730383 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2730121..2730307 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ62_RS13525	2725578..2728322	+	2745	WP_002411259.1	glycosyl hydrolase family 65 protein	-
QLQ62_RS13530	2728337..2728987	+	651	WP_002389419.1	beta-phosphoglucomutase	-
QLQ62_RS13535	2729407..2730000	+	594	WP_002389391.1	PBECR4 domain-containing protein	-
-	2730121..2730307	+	187	-	-	Antitoxin
QLQ62_RS13540	2730240..2730383	-	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
QLQ62_RS13545	2730615..2731586	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
QLQ62_RS13550	2731761..2732198	-	438	WP_002389480.1	peptide-methionine (R)-S-oxide reductase MsrB	-
QLQ62_RS13555	2732331..2732885	-	555	WP_002354869.1	Maf family protein	-
QLQ62_RS13560	2732910..2735042	-	2133	WP_002389406.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T281757 WP_002367458.1 NZ_CP124916:c2730383-2730240 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT281757 NZ_CP124916:2730121-2730307 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin