Detailed information of TA system TA281756

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2657976..2658201
• Replicon: chromosome
• Accession: NZ_CP124916
• Organism: Enterococcus faecalis strain EfsC17

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ62_RS13205
• Protein ID: WP_075551663.1
• Coordinates: 2658100..2658201 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2657976..2658155 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ62_RS13175	2653195..2654148	-	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-
QLQ62_RS13180	2654187..2654942	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ62_RS13185	2654939..2655904	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ62_RS13190	2655904..2656848	-	945	WP_172759402.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ62_RS13195	2657033..2657485	+	453	WP_002389410.1	YueI family protein	-
QLQ62_RS13200	2657667..2657768	-	102	WP_021164441.1	putative holin-like toxin	-
-	2657976..2658155	+	180	-	-	Antitoxin
QLQ62_RS13205	2658100..2658201	-	102	WP_075551663.1	putative holin-like toxin	Toxin
QLQ62_RS13210	2658391..2660661	-	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ62_RS13215	2660832..2661332	+	501	WP_002372831.1	cysteine hydrolase family protein	-
QLQ62_RS13220	2661731..2662627	+	897	WP_002389477.1	YitT family protein	-
QLQ62_RS13225	2662678..2663076	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281756 WP_075551663.1 NZ_CP124916:c2658201-2658100 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 180 bp

>AT281756 NZ_CP124916:2657976-2658155 [Enterococcus faecalis]
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA

Structures

Antitoxin