Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2520986..2521384 Replicon chromosome
Accession NZ_CP124914
Organism Enterococcus faecalis strain EfsC8

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag QLQ37_RS12000 Protein ID WP_023894767.1
Coordinates 2520986..2521090 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2521242..2521384 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ37_RS11985 (2516299) 2516299..2517012 - 714 WP_002354877.1 trehalose operon repressor -
QLQ37_RS11990 (2517273) 2517273..2520017 + 2745 WP_129226010.1 glycosyl hydrolase family 65 protein -
QLQ37_RS11995 (2520032) 2520032..2520682 + 651 WP_016614233.1 beta-phosphoglucomutase -
- (2520866) 2520866..2521053 + 188 NuclAT_4 - -
QLQ37_RS12000 (2520986) 2520986..2521090 - 105 WP_023894767.1 putative holin-like toxin Toxin
- (2521242) 2521242..2521384 + 143 NuclAT_10 - Antitoxin
QLQ37_RS12005 (2521475) 2521475..2521597 - 123 WP_002419628.1 hypothetical protein -
QLQ37_RS12010 (2522390) 2522390..2523361 - 972 WP_002381060.1 ribose-phosphate diphosphokinase -
QLQ37_RS12015 (2523536) 2523536..2523973 - 438 WP_010715474.1 peptide-methionine (R)-S-oxide reductase MsrB -
QLQ37_RS12020 (2524106) 2524106..2524660 - 555 WP_033601100.1 nucleoside triphosphate pyrophosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-34)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3799.63 Da        Isoelectric Point: 10.0079

>T281743 WP_023894767.1 NZ_CP124914:c2521090-2520986 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Download         Length: 105 bp

Antitoxin


Download         Length: 143 bp

>AT281743 NZ_CP124914:2521242-2521384 [Enterococcus faecalis]
TGTGCTATAATGAAAACGAAAAGAGAGATATGCTTCAACATACCTCTCTGATGCAGAGCCGTTTAAGACGGTGACCGATT
TTGTTACAAAAAATAACCGTACCGATCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAACA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References