Detailed information of TA system TA281728

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 433332..433556
• Replicon: chromosome
• Accession: NZ_CP124913
• Organism: Enterococcus faecalis strain EfsC20

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ32_RS02070
• Protein ID: WP_224561205.1
• Coordinates: 433332..433433 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	433378..433556 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ32_RS02050	428659..429057	+	399	WP_002354951.1	glyoxalase	-
QLQ32_RS02055	429108..430004	-	897	WP_002365354.1	YitT family protein	-
QLQ32_RS02060	430194..430700	-	507	WP_002378810.1	cysteine hydrolase family protein	-
QLQ32_RS02065	430871..433141	+	2271	WP_002378809.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ32_RS02070	433332..433433	+	102	WP_224561205.1	putative holin-like toxin	Toxin
-	433378..433556	-	179	-	-	Antitoxin
QLQ32_RS02075	433619..434071	-	453	WP_002378807.1	YueI family protein	-
QLQ32_RS02080	434256..435203	+	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ32_RS02085	435200..436165	+	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ32_RS02090	436162..436917	+	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ32_RS02095	436956..437909	+	954	WP_002359060.1	siderophore ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3629.37 Da
• Isoelectric Point: 4.5869

>T281728 WP_224561205.1 NZ_CP124913:433332-433433 [Enterococcus faecalis]
MSIEATLELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 179 bp

>AT281728 NZ_CP124913:c433556-433378 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCG
AAAATCAGTAGTGCAACAA

Structures

Antitoxin