Detailed information of TA system TA281709

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2732125..2732609
• Replicon: chromosome
• Accession: NZ_CP124911
• Organism: Enterococcus faecalis strain EfsC61

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ53_RS13515
• Protein ID: WP_075551663.1
• Coordinates: 2732125..2732226 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2732400..2732609 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ53_RS13490	2727650..2728603	-	954	WP_010785614.1	siderophore ABC transporter substrate-binding protein	-
QLQ53_RS13495	2728642..2729397	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ53_RS13500	2729394..2730359	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ53_RS13505	2730356..2731303	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ53_RS13510	2731488..2731940	+	453	WP_002354958.1	YueI family protein	-
QLQ53_RS13515	2732125..2732226	-	102	WP_075551663.1	putative holin-like toxin	Toxin
-	2732400..2732609	+	210	-	-	Antitoxin
QLQ53_RS13520	2732558..2732659	-	102	WP_075551663.1	putative holin-like toxin	-
QLQ53_RS13525	2732991..2733092	-	102	WP_075551663.1	putative holin-like toxin	-
QLQ53_RS13530	2733282..2735552	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ53_RS13535	2735786..2736223	+	438	WP_010785615.1	cysteine hydrolase family protein	-
QLQ53_RS13540	2736622..2737518	+	897	WP_002365354.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281709 WP_075551663.1 NZ_CP124911:c2732226-2732125 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT281709 NZ_CP124911:2732400-2732609 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin