Detailed information of TA system TA281696

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 70415..70629
• Replicon: plasmid p2_EfsC33_rep9b
• Accession: NZ_CP124910
• Organism: Enterococcus faecalis strain EfsC33

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: QLQ33_RS15190
• Protein ID: WP_002360667.1
• Coordinates: 70415..70525 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	70565..70629 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ33_RS15145	65600..65806	+	207	Protein_69	transposase	-
QLQ33_RS15150	66336..66956	+	621	WP_002367819.1	recombinase family protein	-
QLQ33_RS15155	66946..67260	+	315	WP_048953689.1	hypothetical protein	-
QLQ33_RS15160	67254..67478	+	225	WP_002383635.1	ultraviolet resistance protein UvrA repressor UvrC	-
QLQ33_RS15165	67539..67748	+	210	WP_002383636.1	hypothetical protein	-
QLQ33_RS15170	67910..68062	+	153	WP_225850000.1	DUF6440 family protein	-
QLQ33_RS15175	68489..69817	+	1329	WP_002400994.1	ultraviolet resistance protein UvrA	-
QLQ33_RS15180	69814..70164	+	351	WP_002400993.1	hypothetical protein	-
QLQ33_RS15185	70121..70333	+	213	WP_002360669.1	hypothetical protein	-
QLQ33_RS15190	70415..70525	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	70565..70629	-	65	-	-	Antitoxin
QLQ33_RS15195	70765..71061	+	297	WP_002360665.1	replication control protein PrgN	-
QLQ33_RS15200	71315..72097	+	783	WP_002360664.1	ParA family protein	-
QLQ33_RS15205	72090..72446	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	prgB/asc10	1..72705	72705

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T281696 WP_002360667.1 NZ_CP124910:70415-70525 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT281696 NZ_CP124910:c70629-70565 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin