Detailed information of TA system TA281694

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-ratA/Fst(toxin)
• Location: 102052..102293
• Replicon: plasmid p1_EfsC33_rep9a
• Accession: NZ_CP124909
• Organism: Enterococcus faecalis strain EfsC33

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: QLQ33_RS14780
• Protein ID: WP_002360667.1
• Coordinates: 102052..102162 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	102202..102293 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ33_RS14760 (99642)	99642..100247	+	606	WP_000238804.1	recombinase family protein	-
QLQ33_RS14765 (100294)	100294..101454	+	1161	WP_267594822.1	Y-family DNA polymerase	-
QLQ33_RS14770 (101451)	101451..101801	+	351	WP_002400993.1	hypothetical protein	-
QLQ33_RS14775 (101758)	101758..101970	+	213	WP_002360669.1	hypothetical protein	-
QLQ33_RS14780 (102052)	102052..102162	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (102202)	102202..102293	-	92	NuclAT_0	-	Antitoxin
- (102202)	102202..102293	-	92	NuclAT_0	-	Antitoxin
- (102202)	102202..102293	-	92	NuclAT_0	-	Antitoxin
- (102202)	102202..102293	-	92	NuclAT_0	-	Antitoxin
QLQ33_RS14785 (102402)	102402..102692	+	291	WP_049084802.1	hypothetical protein	-
QLQ33_RS14790 (102796)	102796..103167	-	372	WP_000049959.1	replication-associated protein RepC	-
QLQ33_RS14795 (103160)	103160..104005	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	ant(6)-Ia / aph(3')-III / erm(B)	cylR2 / cylR1 / cylL / cylS / cylM / cylB / cylA / cylI / asa1	1..104476	104476

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T281694 WP_002360667.1 NZ_CP124909:102052-102162 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 92 bp

>AT281694 NZ_CP124909:c102293-102202 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin