281690

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2817550..2817886 Replicon chromosome
Accession NZ_CP124908
Organism Enterococcus faecalis strain EfsC33

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag QLQ33_RS13640 Protein ID WP_002396786.1
Coordinates 2817550..2817693 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2817837..2817886 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ33_RS13620 (2812667) 2812667..2812882 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
QLQ33_RS13625 (2813021) 2813021..2814013 + 993 WP_023894581.1 biotin--[acetyl-CoA-carboxylase] ligase -
QLQ33_RS13630 (2814277) 2814277..2814915 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
QLQ33_RS13635 (2815601) 2815601..2817217 + 1617 WP_047648929.1 phosphatase PAP2/LCP family protein -
QLQ33_RS13640 (2817550) 2817550..2817693 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2817837) 2817837..2817886 + 50 NuclAT_11 - Antitoxin
- (2817625) 2817625..2817887 - 263 NuclAT_8 - -
QLQ33_RS13645 (2817888) 2817888..2822579 - 4692 WP_049098584.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T281690 WP_002396786.1 NZ_CP124908:2817550-2817693 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 50 bp

>AT281690 NZ_CP124908:2817837-2817886 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References