Detailed information of TA system TA281675

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2619552..2619812
• Replicon: chromosome
• Accession: NZ_CP124908
• Organism: Enterococcus faecalis strain EfsC33

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ33_RS12745
• Protein ID: WP_075551663.1
• Coordinates: 2619711..2619812 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2619552..2619762 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ33_RS12720 (2615236)	2615236..2616189	-	954	WP_002394760.1	siderophore ABC transporter substrate-binding protein	-
QLQ33_RS12725 (2616228)	2616228..2616983	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ33_RS12730 (2616980)	2616980..2617945	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ33_RS12735 (2617942)	2617942..2618889	-	948	WP_002359058.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ33_RS12740 (2619074)	2619074..2619526	+	453	WP_002359057.1	YueI family protein	-
- (2619552)	2619552..2619762	+	211	NuclAT_4	-	Antitoxin
- (2619589)	2619589..2619766	+	178	NuclAT_12	-	-
QLQ33_RS12745 (2619711)	2619711..2619812	-	102	WP_075551663.1	putative holin-like toxin	Toxin
QLQ33_RS12750 (2620001)	2620001..2622271	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ33_RS12755 (2622442)	2622442..2622942	+	501	WP_010709949.1	cysteine hydrolase family protein	-
QLQ33_RS12760 (2623245)	2623245..2624141	+	897	WP_002354953.1	YitT family protein	-
QLQ33_RS12765 (2624192)	2624192..2624590	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281675 WP_075551663.1 NZ_CP124908:c2619812-2619711 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 211 bp

>AT281675 NZ_CP124908:2619552-2619762 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAACA
CCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGT
TATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin