281672

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 569500..569732 Replicon chromosome
Accession NZ_CP124908
Organism Enterococcus faecalis strain EfsC33

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag QLQ33_RS02865 Protein ID WP_002355568.1
Coordinates 569500..569616 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 569527..569732 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ33_RS02855 (564938) 564938..567196 + 2259 WP_002363179.1 DNA helicase PcrA -
QLQ33_RS02860 (567322) 567322..569352 + 2031 WP_010710796.1 NAD-dependent DNA ligase LigA -
QLQ33_RS02865 (569500) 569500..569616 + 117 WP_002355568.1 putative holin-like toxin Toxin
- (569527) 569527..569732 - 206 NuclAT_3 - Antitoxin
QLQ33_RS02870 (569934) 569934..570239 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
QLQ33_RS02875 (570239) 570239..571708 + 1470 WP_033593283.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QLQ33_RS02880 (571708) 571708..573138 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QLQ33_RS02885 (573157) 573157..574245 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T281672 WP_002355568.1 NZ_CP124908:569500-569616 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT281672 NZ_CP124908:c569732-569527 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References