281665

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2638851..2639177 Replicon chromosome
Accession NZ_CP124906
Organism Enterococcus faecalis strain EfsC49

Toxin (Protein)


Gene name txpA Uniprot ID A0A3N3Z2N6
Locus tag QLQ59_RS12695 Protein ID WP_073340360.1
Coordinates 2639037..2639177 (+) Length 47 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2638851..2639035 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ59_RS12670 2633897..2634112 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
QLQ59_RS12675 2634251..2635243 + 993 WP_002354765.1 biotin--[acetyl-CoA-carboxylase] ligase -
QLQ59_RS12680 2635507..2636136 - 630 WP_002354763.1 lytic polysaccharide monooxygenase -
QLQ59_RS12685 2636829..2638445 + 1617 Protein_2470 phosphatase PAP2/LCP family protein -
QLQ59_RS12690 2638775..2638918 + 144 WP_002392818.1 type I toxin-antitoxin system toxin PepG1 -
- 2638851..2639035 - 185 - - Antitoxin
QLQ59_RS12695 2639037..2639177 + 141 WP_073340360.1 putative holin-like toxin Toxin
QLQ59_RS12700 2639368..2642364 - 2997 WP_002385134.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-46)


Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 5218.33 Da        Isoelectric Point: 10.3265

>T281665 WP_073340360.1 NZ_CP124906:2639037-2639177 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 141 bp

Antitoxin


Download         Length: 185 bp

>AT281665 NZ_CP124906:c2639035-2638851 [Enterococcus faecalis]
TGCTACAATAGAGATGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3N3Z2N6

Antitoxin

Download structure file

References