Detailed information of TA system TA281663

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2638775..2639035
• Replicon: chromosome
• Accession: NZ_CP124906
• Organism: Enterococcus faecalis strain EfsC49

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ59_RS12690
• Protein ID: WP_002392818.1
• Coordinates: 2638775..2638918 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2638851..2639035 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ59_RS12670	2633897..2634112	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
QLQ59_RS12675	2634251..2635243	+	993	WP_002354765.1	biotin--[acetyl-CoA-carboxylase] ligase	-
QLQ59_RS12680	2635507..2636136	-	630	WP_002354763.1	lytic polysaccharide monooxygenase	-
QLQ59_RS12685	2636829..2638445	+	1617	Protein_2470	phosphatase PAP2/LCP family protein	-
QLQ59_RS12690	2638775..2638918	+	144	WP_002392818.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	2638851..2639035	-	185	-	-	Antitoxin
QLQ59_RS12695	2639037..2639177	+	141	WP_073340360.1	putative holin-like toxin	-
QLQ59_RS12700	2639368..2642364	-	2997	WP_002385134.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5344.49 Da
• Isoelectric Point: 10.6323

>T281663 WP_002392818.1 NZ_CP124906:2638775-2638918 [Enterococcus faecalis]
MNVSTKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT281663 NZ_CP124906:c2639035-2638851 [Enterococcus faecalis]
TGCTACAATAGAGATGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin