Detailed information of TA system TA281655

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2487688..2488172
• Replicon: chromosome
• Accession: NZ_CP124906
• Organism: Enterococcus faecalis strain EfsC49

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ59_RS12000
• Protein ID: WP_075551663.1
• Coordinates: 2487688..2487789 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2487963..2488172 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ59_RS11975	2483213..2484166	-	954	WP_002354964.1	siderophore ABC transporter substrate-binding protein	-
QLQ59_RS11980	2484205..2484960	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ59_RS11985	2484957..2485922	-	966	WP_002354961.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ59_RS11990	2485919..2486866	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ59_RS11995	2487051..2487503	+	453	WP_002354958.1	YueI family protein	-
QLQ59_RS12000	2487688..2487789	-	102	WP_075551663.1	putative holin-like toxin	Toxin
-	2487963..2488172	+	210	-	-	Antitoxin
QLQ59_RS12005	2488121..2488222	-	102	WP_075551663.1	putative holin-like toxin	-
QLQ59_RS12010	2488412..2490682	-	2271	WP_002392683.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ59_RS12015	2490853..2491353	+	501	WP_002354954.1	cysteine hydrolase family protein	-
QLQ59_RS12020	2491900..2492796	+	897	WP_010784075.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281655 WP_075551663.1 NZ_CP124906:c2487789-2487688 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT281655 NZ_CP124906:2487963-2488172 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin