Detailed information of TA system TA281648

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 2715253..2715448
• Replicon: chromosome
• Accession: NZ_CP124905
• Organism: Enterococcus faecalis strain EfsC85

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: QLQ41_RS12875
• Protein ID: WP_015543884.1
• Coordinates: 2715253..2715348 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2715383..2715448 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ41_RS12855	2710430..2711545	+	1116	WP_002377910.1	FAD-dependent oxidoreductase	-
QLQ41_RS12860	2711614..2712768	-	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
QLQ41_RS12865	2712783..2713220	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
QLQ41_RS12870	2713235..2715007	-	1773	WP_002391520.1	PTS mannitol-specific transporter subunit IIBC	-
QLQ41_RS12875	2715253..2715348	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2715383..2715448	-	66	-	-	Antitoxin
QLQ41_RS12880	2715606..2716040	-	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
QLQ41_RS12885	2716051..2718084	-	2034	WP_002355275.1	BglG family transcription antiterminator	-
QLQ41_RS12890	2718075..2719817	-	1743	WP_002401739.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T281648 WP_015543884.1 NZ_CP124905:2715253-2715348 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 66 bp

>AT281648 NZ_CP124905:c2715448-2715383 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin