Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2400470..2400702 Replicon chromosome
Accession NZ_CP124905
Organism Enterococcus faecalis strain EfsC85

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag QLQ41_RS11380 Protein ID WP_002355568.1
Coordinates 2400586..2400702 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2400470..2400675 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ41_RS11360 2395957..2397045 - 1089 WP_002355572.1 diacylglycerol kinase -
QLQ41_RS11365 2397064..2398494 - 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QLQ41_RS11370 2398494..2399963 - 1470 WP_002358701.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QLQ41_RS11375 2399963..2400268 - 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
QLQ41_RS11380 2400586..2400702 - 117 WP_002355568.1 putative holin-like toxin Toxin
QLQ41_RS11385 2400850..2402880 - 2031 WP_002378031.1 NAD-dependent DNA ligase LigA -
QLQ41_RS11390 2403006..2405264 - 2259 WP_002363179.1 DNA helicase PcrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T281645 WP_002355568.1 NZ_CP124905:c2400702-2400586 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT281645 NZ_CP124905:2400470-2400675 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References