Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 256171..256508 Replicon chromosome
Accession NZ_CP124905
Organism Enterococcus faecalis strain EfsC85

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag QLQ41_RS01205 Protein ID WP_002396786.1
Coordinates 256365..256508 (-) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 256171..256433 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ41_RS01200 251479..256170 + 4692 Protein_228 WxL domain-containing protein -
- 256171..256433 + 263 - - Antitoxin
QLQ41_RS01205 256365..256508 - 144 WP_002396786.1 putative holin-like toxin Toxin
QLQ41_RS01210 256840..258456 - 1617 WP_002378864.1 phosphatase PAP2/LCP family protein -
QLQ41_RS01215 259141..259779 + 639 WP_002378863.1 lytic polysaccharide monooxygenase -
QLQ41_RS01220 259946..260938 - 993 WP_282897387.1 biotin--[acetyl-CoA-carboxylase] ligase -
QLQ41_RS01225 261077..261292 + 216 WP_002354768.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T281636 WP_002396786.1 NZ_CP124905:c256508-256365 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT281636 NZ_CP124905:256171-256433 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References