Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 516349..516575 Replicon chromosome
Accession NZ_CP124901
Organism Enterococcus faecalis strain EfsC94

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag QLQ35_RS02535 Protein ID WP_219843903.1
Coordinates 516349..516459 (+) Length 37 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 516370..516575 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ35_RS02525 (511781) 511781..514039 + 2259 WP_002363179.1 DNA helicase PcrA -
QLQ35_RS02530 (514165) 514165..516195 + 2031 WP_002358699.1 NAD-dependent DNA ligase LigA -
QLQ35_RS02535 (516349) 516349..516459 + 111 WP_219843903.1 putative holin-like toxin Toxin
- (516370) 516370..516575 - 206 NuclAT_3 - Antitoxin
QLQ35_RS02540 (516777) 516777..517082 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
QLQ35_RS02545 (517082) 517082..518551 + 1470 WP_002361259.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QLQ35_RS02550 (518551) 518551..519981 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QLQ35_RS02555 (520000) 520000..521088 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-33)


Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 3805.59 Da        Isoelectric Point: 5.9482

>T281612 WP_219843903.1 NZ_CP124901:516349-516459 [Enterococcus faecalis]
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 111 bp

Antitoxin


Download         Length: 206 bp

>AT281612 NZ_CP124901:c516575-516370 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References