Detailed information of TA system TA281610

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2669633..2670217
• Replicon: chromosome
• Accession: NZ_CP124900
• Organism: Enterococcus faecalis strain EfsC108

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ58_RS12690
• Protein ID: WP_002368507.1
• Coordinates: 2669633..2669830 (+)
• Length: 66 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2669980..2670217 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ58_RS12680	2664999..2665143	+	145	Protein_2472	putative holin-like toxin	-
QLQ58_RS12685	2665332..2669090	-	3759	WP_282897146.1	WxL domain-containing protein	-
QLQ58_RS12690	2669633..2669830	+	198	WP_002368507.1	type I toxin-antitoxin system toxin PepG1	Toxin
QLQ58_RS12695	2670217..2673276	-	3060	WP_282897147.1	WxL domain-containing protein	-
-	2669763..2669949	-	187	-	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (32-65)

Sequences

Toxin

Protein

• Length: 66 a.a.
• Molecular weight: 7557.14 Da
• Isoelectric Point: 10.6710

>T281610 WP_002368507.1 NZ_CP124900:2669633-2669830 [Enterococcus faecalis]
MCREVMAVAIQSEREVMRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 198 bp

Antitoxin

Nucleotide

• Length: 238 bp

>AT281610 NZ_CP124900:c2670217-2669980 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGGTCGTTGTGCTATA
ATAGCATTGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCAATTGTATTATTT
AAAAATAACCGTACTGGTCAAAGTAAACGGTTATTTTTTCTTGTCTTCTTTAACAACCTTTAGGATTCCGAAGATTAA

Structures

Antitoxin