Detailed information of TA system TA281607

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2669431..2669830
• Replicon: chromosome
• Accession: NZ_CP124900
• Organism: Enterococcus faecalis strain EfsC108

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ58_RS12690
• Protein ID: WP_002368507.1
• Coordinates: 2669633..2669830 (+)
• Length: 66 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2669431..2669575 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ58_RS12680	2664999..2665143	+	145	Protein_2472	putative holin-like toxin	-
QLQ58_RS12685	2665332..2669090	-	3759	WP_282897146.1	WxL domain-containing protein	-
QLQ58_RS12690	2669633..2669830	+	198	WP_002368507.1	type I toxin-antitoxin system toxin PepG1	Toxin
QLQ58_RS12695	2670217..2673276	-	3060	WP_282897147.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (32-65)

Sequences

Toxin

Protein

• Length: 66 a.a.
• Molecular weight: 7557.14 Da
• Isoelectric Point: 10.6710

>T281607 WP_002368507.1 NZ_CP124900:2669633-2669830 [Enterococcus faecalis]
MCREVMAVAIQSEREVMRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 198 bp

Antitoxin

Nucleotide

• Length: 145 bp

>AT281607 NZ_CP124900:c2669575-2669431 [Enterococcus faecalis]
TTGTGCTATAATGATAATGAAAAGAGAGATATGCGCTAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCATG
TTAATTATTTAAAAATAACCGTACTCGGTCAAAGTAGACGGTTATTTTTCTTGTCATTTTTAAGC

Structures

Antitoxin