Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2561296..2561571 Replicon chromosome
Accession NZ_CP124900
Organism Enterococcus faecalis strain EfsC108

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag QLQ58_RS12210 Protein ID WP_282897135.1
Coordinates 2561428..2561571 (-) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2561296..2561495 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ58_RS12190 2556343..2557056 - 714 WP_002354877.1 trehalose operon repressor -
QLQ58_RS12195 2557318..2560062 + 2745 WP_282897134.1 glycosyl hydrolase family 65 protein -
QLQ58_RS12200 2560077..2560727 + 651 WP_002354875.1 beta-phosphoglucomutase -
QLQ58_RS12205 2561052..2561156 - 105 WP_023894767.1 putative holin-like toxin -
QLQ58_RS12210 2561428..2561571 - 144 WP_282897135.1 type I toxin-antitoxin system toxin PepG1 Toxin
QLQ58_RS12215 2561805..2562776 - 972 WP_002381060.1 ribose-phosphate diphosphokinase -
QLQ58_RS12220 2562951..2563388 - 438 WP_002354871.1 peptide-methionine (R)-S-oxide reductase MsrB -
QLQ58_RS12225 2563521..2564075 - 555 WP_282897136.1 Maf family protein -
QLQ58_RS12230 2564100..2566232 - 2133 WP_282897137.1 DNA mismatch repair endonuclease MutL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5279.40 Da        Isoelectric Point: 10.6867

>T281605 WP_282897135.1 NZ_CP124900:c2561571-2561428 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGIFTIALIALIVKLLKNDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 200 bp

>AT281605 NZ_CP124900:2561296-2561495 [Enterococcus faecalis]
TTTTTAGGGAATTGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGA
CGGTGACTTTTTGAATTATTTAAAAATAACCGTACTCGGTCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAAGCAAT
TTCACAATCAGTGCAATCAAAGCAATGGTAAATATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References